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The pathophysiology of circulating corticotropin-releasing hormone-binding protein levels in the human.

Abstract:

To establish the factors that modulate circulating CRH-binding protein (CRH-BP) levels, we measured plasma CRH-BP in patients with a variety of endocrine and systemic disorders. CRH-BP was measured by RIA. Young women have higher plasma levels of CRH-BP than young men [females (n = 18), mean +/- SEM, 145 +/- 7; males (n = 20), 99 +/- 6 ng/mL; P < 0.0001], but levels do not fall with the menopause or vary during the menstrual cycle and are unaffected by estrogen replacement therapy. Levels ...

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Publication status:
Published

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Publisher copy:
10.1210/jc.83.5.1611

Authors


Trainer, PJ More by this author
Korbonits, M More by this author
Popovic, V More by this author
Stewart, PM More by this author
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Journal:
The Journal of clinical endocrinology and metabolism
Volume:
83
Issue:
5
Pages:
1611-1614
Publication date:
1998-05-05
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
URN:
uuid:9d12c8f7-d10c-4f4e-8960-29fa6bb03d97
Source identifiers:
138242
Local pid:
pubs:138242

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