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Journal article

Differences in phenotype and function between spontaneously occurring melan-A-, tyrosinase- and influenza matrix peptide-specific CTL in HLA-A*0201 melanoma patients.

Abstract:

Melanoma-specific T cells can occur spontaneously or in response to vaccination or other therapies, but the frequency is much lower than observed in viral infections. The presence of tumor-specific T cells does not necessarily translate into clinical regressions for a variety of reasons such as an insufficient frequency, activation state or homing capacity of the T cells or escape strategies of the tumor. Having screened melanoma patients prior to inclusion in vaccination trials for spontaneo...

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Publication status:
Published

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Publisher copy:
10.1002/ijc.20901

Authors


Berger, TG More by this author
Schuler-Thurner, B More by this author
Schultz, ES More by this author
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Journal:
International journal of cancer. Journal international du cancer
Volume:
115
Issue:
3
Pages:
450-455
Publication date:
2005-06-05
DOI:
EISSN:
1097-0215
ISSN:
0020-7136
URN:
uuid:9cb3e13f-d601-4391-8042-1540c1fd7d78
Source identifiers:
32979
Local pid:
pubs:32979

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