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Thesis

Perisomatic-targeting interneurons control the initiation of hippocampal population bursts

Abstract:

Replay of spike sequences can be seen during sharp wave – ripple population burst activity in the hippocampus. It is thought that this activity, which occurs during rest and sleep, is involved in memory consolidation. The cellular mechanisms underlying the initiation of these replay events are not well understood. To investigate this, a hippocampal slice model, showing spontaneous sharp wave – ripple activity, and a combination of planar multi-electrode array recordings and whole-cell patch-c...

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Institution:
University of Oxford
Research group:
Neuronal Oscillations Group
Oxford college:
St John's College
Department:
Medical Sciences Division - Pharmacology
Role:
Author

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Role:
Supervisor
Role:
Supervisor
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Funding agency for:
Tommas Jan Ellender
Publication date:
2009
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:9c9c34af-a20f-4c9c-9cb3-85f110a1e38e
Local pid:
ora:2917

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