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The fitness of human translocation carriers.

Abstract:
A simple method to estimate the mean fitness of human translocation carriers is described. The method is based on information about the inheritance pattern of the translocations. This kind of data can be obtained from the surveys of the chromosome constitutions of new-born babies. The following fitness estimates are obtained: D/D translocation carriers, 0-94; D/G translocation carriers, 0-83; and reciprocal translocation carriers, 0-67. The estimates are rather uncertain due to the scarcity of information, but they are consistent with the expected results. More accurate estimates will be obtained in the future when more data on translocation carriers are available and the cytological classification of the different translocations becomes more exact.

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Publisher copy:
10.1111/j.1469-1809.1976.tb00188.x

Authors



Journal:
Annals of human genetics More from this journal
Volume:
40
Issue:
2
Pages:
253-257
Publication date:
1976-11-01
DOI:
EISSN:
1469-1809
ISSN:
0003-4800


Language:
English
Keywords:
Pubs id:
pubs:487534
UUID:
uuid:9c927be4-8df5-4a6a-a510-e54e0789d201
Local pid:
pubs:487534
Source identifiers:
487534
Deposit date:
2014-10-29

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