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Journal article

Effect of ret/PTC 1 rearrangement on transcription and post-transcriptional regulation in a papillary thyroid carcinoma model.

Abstract:

BACKGROUND: microRNAs (miRNAs) are a group of non-coding single stranded RNAs measuring approximately 22 nt in length that have been found to control cell growth, differentiation and apoptosis. miRNAs negatively regulate their target genes and recently have been implicated in tumourigenesis. Furthermore, miRNA expression profiling correlates with various cancers, with these genes thought to act as both tumour suppressors and oncogenes. ret/PTC 1 is an oncogene with constitutive kinase activi...

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Publication status:
Published

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Publisher copy:
10.1186/1476-4598-5-70

Authors


Denning, K More by this author
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Journal:
Molecular cancer
Volume:
5
Pages:
70
Publication date:
2006
DOI:
EISSN:
1476-4598
ISSN:
1476-4598
URN:
uuid:9c6c85dd-bae2-438f-88a6-0d3da5f122fe
Source identifiers:
441501
Local pid:
pubs:441501

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