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Targets of statin therapy: LDL cholesterol, non-HDL cholesterol, and apolipoprotein B in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS).

Abstract:

BACKGROUND: LDL can vary considerably in its cholesterol content; thus, lowering LDL cholesterol (LDLC) as a goal of statin treatment implies the existence of considerable variation in the extent to which statin treatment removes circulating LDL particles. This consideration is particularly applicable in diabetes mellitus, in which LDL is frequently depleted of cholesterol. METHODS: Type 2 diabetes patients randomly allocated to 10 mg/day atorvastatin (n = 1154) or to placebo (n = 1196) for ...

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Journal:
Clinical chemistry
Volume:
55
Issue:
3
Pages:
473-480
Publication date:
2009-03-05
DOI:
EISSN:
1530-8561
ISSN:
0009-9147
URN:
uuid:9c5d6f1f-b043-4aa7-92a5-248b832102bd
Source identifiers:
72706
Local pid:
pubs:72706

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