Thesis
Rare genetic variants and susceptibility to severe bacterial diseases
- Abstract:
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Infectious diseases are a major cause of morbidity and mortality worldwide. Streptococcus pneumoniae
and Neisseria meningitidis are major causes of severe bacterial disease which can manifest as invasive disease such as bacteraemia and meningitis. Exposure to these pathogens is relatively widespread, yet only a minority of individuals develop invasive disease. A host genetic component to infectious disease susceptibility has been implied from twin and adoptee studies. A r... Expand abstract
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Funding
Medical Research Council
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:9c5745f9-50f9-469a-8771-2e49e75db7ac
- Deposit date:
- 2017-04-25
Terms of use
- Copyright holder:
- Ndungu, A
- Copyright date:
- 2015
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