- Abstract:
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Infectious diseases are a major cause of morbidity and mortality worldwide. Streptococcus pneumoniae
and Neisseria meningitidis are major causes of severe bacterial disease which can manifest as invasive disease such as bacteraemia and meningitis. Exposure to these pathogens is relatively widespread, yet only a minority of individuals develop invasive disease. A host genetic component to infectious disease susceptibility has been implied from twin and adoptee studies. A r... Expand abstract - Files:
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- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
- English
- Keywords:
- Subjects:
- Copyright date:
- 2015
Thesis
Rare genetic variants and susceptibility to severe bacterial diseases
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