- Abstract:
-
Immunological synapses are specialized intercellular contacts formed by several types of immune cells in contact with target cells or antigen-presenting cells. A late-stage immune synapse is commonly a bulls-eye pattern of immune cell receptor-ligand pairs surrounded by integrin complexes. Based on crystal structures, the intermembrane distance would be ∼15 nm for many immune cell receptor-ligand pairs, but ∼40 nm for integrin-ligand pairs. Close proximity of these two classes of intermembran...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.bpj.2011.05.013
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- Journal:
- Biophysical journal
- Volume:
- 100
- Issue:
- 12
- Pages:
- 2865-2874
- Publication date:
- 2011-06-05
- DOI:
- EISSN:
-
1542-0086
- ISSN:
-
0006-3495
- URN:
-
uuid:9c464fb5-8617-447d-b8d1-54e2dfe21164
- Source identifiers:
-
166528
- Local pid:
- pubs:166528
- Copyright date:
- 2011
Journal article
Mechanisms for size-dependent protein segregation at immune synapses assessed with molecular rulers.
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