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Fluorescence imaging of MACPF/CDC proteins: new techniques and their application.

Abstract:
Structural and biochemical investigations have helped illuminate many of the important details of MACPF/CDC pore formation. However, conventional techniques are limited in their ability to tackle many of the remaining key questions, and new biophysical techniques might provide the means to improve our understanding. Here we attempt to identify the properties of MACPF/CDC proteins that warrant further study, and explore how new developments in fluorescence imaging are able to probe these properties.

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Authors


Senior, MJ More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Physical and Theoretical Chem
Journal:
Sub-cellular biochemistry
Volume:
80
Pages:
293-319
Publication date:
2014
DOI:
ISSN:
0306-0225
URN:
uuid:9c439246-5a2e-4c2d-88f4-24e741b2320b
Source identifiers:
465132
Local pid:
pubs:465132

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