Liquid-vapor oscillations of water in hydrophobic nanopores.

Journal article

Water plays a key role in biological membrane transport. In ion channels and water-conducting pores (aquaporins), one-dimensional confinement in conjunction with strong surface effects changes the physical behavior of water. In molecular dynamics simulations of water in short (0.8 nm) hydrophobic pores the water density in the pore fluctuates on a nanosecond time scale. In long simulations (460 ns in total) at pore radii ranging from 0.35 to 1.0 nm we quantify the kinetics of oscillations bet...

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Authors: Beckstein, O; Sansom, MS

• Publication status: Published
• Journal: Proceedings of the National Academy of Sciences of the United States of America
• Volume: 100
• Issue: 12
• Pages: 7063-7068
• Publication date: 2003-06-01
• DOI: 10.1073/pnas.1136844100
• EISSN: 1091-6490
• ISSN: 0027-8424
• Language: English
• Keywords: Kinetics; Aquaporins; Biophysics; Receptors, Nicotinic; Models, Biological; Gramicidin; Biological Transport, Active; Nanotechnology; Biophysical Phenomena; Cell Membrane; Thermodynamics; Water; Oscillometry; Hydrophobic and Hydrophilic Interactions