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Journal article

Rheumatoid arthritis susceptibility and interleukin 10: a study of two ethnically diverse populations.

Abstract:

INTRODUCTION: IL-10 is an immunoregulatory cytokine which may modulate disease expression in rheumatoid arthritis (RA). The IL-10 gene is highly polymorphic with a number of single nucleotide polymorphisms in the promoter region and two microsatellite loci, IL10.R and IL10.G, 4 kb and 1.1 kb 5' of the transcription initiation site. It has been reported that allele 2 of the IL10.R microsatellite (IL10.R2) is associated with increased IL-10 secretion and IL10.R3 with reduced secretion. Subseque...

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Publication status:
Published

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Publisher copy:
10.1093/rheumatology/keg054

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Journal:
Rheumatology (Oxford, England)
Volume:
42
Issue:
1
Pages:
149-153
Publication date:
2003-01-05
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
URN:
uuid:9c0cf363-518c-4a26-8d5b-6e4d6ba2303e
Source identifiers:
108525
Local pid:
pubs:108525

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