- Abstract:
- iMembrane is a homology-based method, which predicts a membrane protein's position within a lipid bilayer. It projects the results of coarse-grained molecular dynamics simulations onto any membrane protein structure or sequence provided by the user. iMembrane is simple to use and is currently the only computational method allowing the rapid prediction of a membrane protein's lipid bilayer insertion. Bilayer insertion data are essential in the accurate structural modelling of membrane proteins or the design of drugs that target them.
- Publication status:
- Published
- Files:
-
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(pdf, 85.6KB)
-
- Publisher copy:
- 10.1093/bioinformatics/btp102
-
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- Journal:
- Bioinformatics (Oxford, England)
- Volume:
- 25
- Issue:
- 8
- Pages:
- 1086-1088
- Publication date:
- 2009-04-05
- DOI:
- EISSN:
-
1367-4811
- ISSN:
-
1367-4803
- URN:
-
uuid:9bf5935d-4b36-4a62-a73b-96fefa8f029f
- Source identifiers:
-
97637
- Local pid:
- pubs:97637
- Language:
- English
- Keywords:
- Copyright date:
- 2009
Journal article
iMembrane: homology-based membrane-insertion of proteins.
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