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Journal article

Enhanced protein kinase B/Akt signalling in pituitary tumours.

Abstract:

Pituitary tumours have previously been shown to harbour several abnormalities that cause deregulation of the cell cycle, particularly down-regulation of expression of the cyclin-dependent kinase inhibitor p27. However, it has been unclear whether these are the primary initiating events, or are secondary to other more proximate alterations in signalling pathways. In other cellular systems the Akt signalling pathway has been associated with downstream modulation of cell-cycle control. The aim o...

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Publication status:
Published

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Publisher copy:
10.1677/erc.1.00949

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Journal:
Endocrine-related cancer
Volume:
12
Issue:
2
Pages:
423-433
Publication date:
2005-06-05
DOI:
EISSN:
1479-6821
ISSN:
1351-0088
URN:
uuid:9bf04d7b-4ec3-48a3-b65d-34c2c0d99d31
Source identifiers:
138389
Local pid:
pubs:138389

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