Journal article
Neuropathological evidence of body-first vs. brain-first Lewy body disease
- Abstract:
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Aggregation of alpha-synuclein into inclusion bodies, termed Lewy pathology, is a defining feature of Parkinson's disease (PD) and Dementia with Lewy bodies (DLB). In the majority of post mortem cases, the distribution of Lewy pathology seems to follow two overarching patterns: a caudo-rostral pattern with relatively more pathology in the brainstem than in the telencephalon, and an amygdala-centered pattern with the most abundant pathology in the “center of the brain”, including the amygdala,...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 4.6MB, Terms of use)
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- Publisher copy:
- 10.1016/j.nbd.2021.105557
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Bibliographic Details
- Publisher:
- Elsevier
- Journal:
- Neurobiology of Disease More from this journal
- Volume:
- 161
- Article number:
- 105557
- Publication date:
- 2021-11-08
- Acceptance date:
- 2021-11-06
- DOI:
- ISSN:
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0969-9961
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1235863
- Local pid:
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pubs:1235863
- Deposit date:
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2022-01-28
Terms of use
- Copyright holder:
- Borghammer et al.
- Copyright date:
- 2021
- Rights statement:
- © 2021 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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