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Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

Abstract:

Associations between single nucleotide polymorphisms (snps) at 5p15 and multiple cancer types have been reported. we have previously shown evidence for a strong association between prostate cancer (prca) risk and rs2242652 at 5p15, intronic in the telomerase reverse transcriptase (tert) gene that encodes tert. to comprehensively evaluate the association between genetic variation across this region and prca, we performed a fine-mapping analysis by genotyping 134 snps using a custom illumina is...

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Publisher copy:
10.1093/hmg/ddt095

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Journal:
Human Molecular Genetics
Volume:
22
Issue:
12
Pages:
2520-2528
Publication date:
2013-06-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:9b8bf844-f917-4b1d-b9e7-cf7c14d0695c
Source identifiers:
403958
Local pid:
pubs:403958
Language:
English

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