Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

Kote-Jarai, Z; Saunders, EJ; Leongamornlert, DA; Tymrakiewicz, M; Dadaev, T; Jugurn-Little, S; Ross-Adams, H; Al Olama, AA; Benlloch, S; Halim, S; Russel, R; Dunning, AM; Luccarini, C; Dennis, J; Neal, DE; Hamdy, FC; Donovan, JL; Muir, K; Giles, GG; Severi, G; Wiklund, F; Gronberg, H; Haiman, CA; Schumacher, F; Henderson, BE; Marchand, LL; Lindstrom, S; Kraft, P; Hunter, DJ; Gapstur, S; Chanock, S; Berndt, SI; Albanes, D; Andriole, G; Schleutker, J; Weischer, M; Canzian, F; Riboli, E; Key, TJ; Travis, RC; Campa, D; Ingles, SA; John, EM; Hayes, RB; Pharoah, P; Khaw, K-T; Stanford, JL; Ostrander, EA; Signorello, LB; Thibodeau, SN; Schaid, D; Maier, C; Vogel, W; Kibel, AS; Cybulski, C; Lubinski, J; Cannon-Albright, L; Brenner, H; Park, JY; Kaneva, R; Batra, J; Spurdle, A; Clements, JA; Teixeira, MR; Govindasami, K; Guy, M; Wilkinson, RA; Sawyer, EJ; Morgan, A; Dicks, E; Baynes, C; Conroy, D; Bojesen, SE; Kaaks, R; Vincent, D; Bacot, F; Tessier, DC; Easton, DF; Eeles, RA

Abstract:

Associations between single nucleotide polymorphisms (snps) at 5p15 and multiple cancer types have been reported. we have previously shown evidence for a strong association between prostate cancer (prca) risk and rs2242652 at 5p15, intronic in the telomerase reverse transcriptase (tert) gene that encodes tert. to comprehensively evaluate the association between genetic variation across this region and prca, we performed a fine-mapping analysis by genotyping 134 snps using a custom illumina is...

Expand abstract

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Kote-Jarai, Z., Saunders, E. J., Leongamornlert, D. A., Tymrakiewicz, M., Dadaev, T., Jugurn-Little, S., Ross-Adams, H., Al Olama, A. A., Benlloch, S., Halim, S., Russel, R., Dunning, A. M., Luccarini, C., Dennis, J., Neal, D. E., Hamdy, F. C., Donovan, J. L., Muir, K., Giles, G. G., … Eeles, R. A. (2013). Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression. Human Molecular Genetics, 22(12), 2520–2528.

MLA Style

Kote-Jarai, Z., et al. “Fine-Mapping Identifies Multiple Prostate Cancer Risk Loci at 5p15, One of Which Associates with TERT Expression.” Human Molecular Genetics, vol. 22, no. 12, 2013, pp. 2520–28.

Chicago Style

Kote-Jarai, Z, EJ Saunders, DA Leongamornlert, M Tymrakiewicz, T Dadaev, S Jugurn-Little, H Ross-Adams, et al. 2013. “Fine-Mapping Identifies Multiple Prostate Cancer Risk Loci at 5p15, One of Which Associates with TERT Expression.” Human Molecular Genetics 22 (12): 2520–28.
Tweet
Print