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Conference item : Abstract

A new pathway for membrane protein insertion at the ER

Abstract:
Membrane protein insertion is an essential cellular process. The broad biophysical and topological range of membrane proteins necessitates multiple insertion pathways, which remain incompletely defined. Here, we have discovered a new membrane protein insertion pathway, identified the class of substrates it handles, explained why other known pathways do not work for these substrates and reconstituted the pathway using purified components.
Publication status:
Published
Peer review status:
Reviewed (other)

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Publisher copy:
10.1091/mbc.e17-10-0618

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; oxford Ludwig Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Role:
Author
Publisher:
American Society for Cell Biology Publisher's website
Host title:
Molecular Biology of the Cell
Journal:
American Society for Cell Biology (ASCB) Annual Meeting (ASCB | EMBO 2017) Journal website
Volume:
28
Issue:
26
Pages:
3727-3895
Publication date:
2018-01-09
Acceptance date:
2017-09-28
DOI:
EISSN:
1939-4586
ISSN:
1059-1524
Source identifiers:
831874
Subtype:
Abstract
Pubs id:
pubs:831874
UUID:
uuid:9b70f81a-0ecf-45f0-8c83-743c8e9c2127
Local pid:
pubs:831874
Deposit date:
2018-04-04

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