- Abstract:
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There are over 120 types of autoantibodies found in the blood of SLE patients against cellular and extracellular components in both their native and posttranslationally modified forms. In recent years, these autoantibodies have provoked interest as initiators of pathology and as biomarkers of disease activity. Often, the host antigens employed in lab-based and commercially developed immunoassays use non-human antigen or non-modified host antigen as a probe for autoantibodies. Here, we describ...
Expand abstract - Publisher copy:
- 10.1007/978-1-4939-0326-9_12
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- Publisher:
- Humana Press Inc.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Volume:
- 1134
- Pages:
- 163-171
- Publication date:
- 2014-01-01
- DOI:
- EISSN:
-
1940-6029
- ISSN:
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1064-3745
- URN:
-
uuid:9b43db3e-99e7-4e54-92f4-8b1311d14af2
- Source identifiers:
-
449044
- Local pid:
- pubs:449044
- Copyright date:
- 2014
Journal article
Detection and characterization of autoantibodies against modified self-proteins in SLE sera after exposure to reactive oxygen and nitrogen species.
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