Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition.

Journal article

CONTEXT: Insulin resistance, which associates with levels of retinol-binding protein 4 (RBP4) and adiponectin, is implicated in the development of polycystic ovary syndrome (PCOS). OBJECTIVE: The objective of the study was to explore the potential contribution of RBP4 and adiponectin in the etiology of PCOS and their relationships with specific fat depot measurements. DESIGN: This was a cross-sectional study. SETTING AND PARTICIPANTS: Serum RBP4 and adiponectin levels were compared between 5...

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Authors: Barber, T; Hazell, M; Christodoulides, C; Golding, S; Alvey, C

• Publication status: Published
• Journal: Journal of clinical endocrinology and metabolism
• Volume: 93
• Issue: 7
• Pages: 2859-2865
• Publication date: 2008-07-01
• DOI: 10.1210/jc.2007-2759
• EISSN: 1945-7197
• ISSN: 0021-972X
• Language: English
• Keywords: Female; Humans; Insulin Resistance; Testosterone; Intra-Abdominal Fat; Adult; Polycystic Ovary Syndrome; Retinol-Binding Proteins, Plasma; Adiponectin