- Abstract:
-
It has been well established that maternal inflammation during pregnancy alters neurological function in the offspring, but its impact on cortical development and long-term consequences on the cytoarchitecture is largely unstudied. Here we report that lipopolysaccharide-induced systemic maternal inflammation in C57Bl/6 mice at embryonic Day 13.5 of pregnancy, as early as 8h after challenge, caused a significant reduction in cell proliferation in the ventricular zone of the developing cerebral...
Expand abstract - Publisher copy:
- 10.1093/brain/awr237
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- Journal:
- Brain
- Volume:
- 134
- Issue:
- 11
- Pages:
- 3236-3248
- Publication date:
- 2011-11-05
- DOI:
- EISSN:
-
1460-2156
- ISSN:
-
0006-8950
- URN:
-
uuid:9acdffdf-ed5c-4ecf-84f3-0fcc31064898
- Source identifiers:
-
206452
- Local pid:
- pubs:206452
- Language:
- English
- Keywords:
- Copyright date:
- 2011
Journal article
Reduced ventricular proliferation in the foetal cortex following maternal inflammation in the mouse
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