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Intercellular Ca2+ signalling: the artery wall.

Abstract:

The fact that many cells in the cardiovascular system are coupled via gap junctions enables direct intercellular Ca2+ signalling. Ca2+ ions and/or inositol trisphosphate (IP3) can pass through these aqueous pores. Cell-cell coupling can occur between cells of the same type, or via special junctions between adjacent cells of different types. Homocellular coupling acts to amplify and prolong Ca2+ signals, whereas heterocellular coupling allows complex interactions between the cells, including t...

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Publisher copy:
10.1006/scdb.2000.0214

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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology, BHF Centre of Research Excellence
Journal:
Seminars in cell and developmental biology
Volume:
12
Issue:
1
Pages:
27-35
Publication date:
2001-02-05
DOI:
EISSN:
1096-3634
ISSN:
1084-9521
URN:
uuid:9a8b7559-2c36-4b63-9933-38cd671ebd79
Source identifiers:
106343
Local pid:
pubs:106343

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