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Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium.

Abstract:

Observational studies have found an inverse association between type 2 diabetes (T2D) and prostate cancer (PCa), and genome-wide association studies have found common variants near 3 loci associated with both diseases. The authors examined whether a genetic background that favors T2D is associated with risk of advanced PCa. Data from the National Cancer Institute's Breast and Prostate Cancer Cohort Consortium, a genome-wide association study of 2,782 advanced PCa cases and 4,458 controls, wer...

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Publication status:
Published

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Publisher copy:
10.1093/aje/kws191

Authors


Machiela, MJ More by this author
Lindström, S More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Cancer Epidemiology Unit
Haiman, CA More by this author
Albanes, D More by this author
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Journal:
American journal of epidemiology
Volume:
176
Issue:
12
Pages:
1121-1129
Publication date:
2012-12-05
DOI:
EISSN:
1476-6256
ISSN:
0002-9262
URN:
uuid:9a81bd25-6f86-401f-bd47-6bf5004c4e9d
Source identifiers:
371426
Local pid:
pubs:371426

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