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Journal article

Diffusion tensor imaging in sporadic and familial (D90A SOD1) forms of amyotrophic lateral sclerosis.

Abstract:

BACKGROUND: The basis of heterogeneity in the clinical presentation and rate of progression of amyotrophic lateral sclerosis (ALS) is poorly understood. OBJECTIVES: To use diffusion tensor imaging as a measure of axonal pathologic features in vivo in ALS and to compare a homogeneous form of familial ALS (homozygous D90A SOD1 [superoxide dismutase 1]) with sporadic ALS. DESIGN: Cross-sectional diffusion tensor imaging study. SETTING: Tertiary referral neurology clinic. PATIENTS: Twenty patient...

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Publication status:
Published

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Publisher copy:
10.1001/archneurol.2008.527

Authors


Stanton, BR More by this author
Shinhmar, D More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Williams, VC More by this author
Williams, SC More by this author
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Journal:
Archives of neurology
Volume:
66
Issue:
1
Pages:
109-115
Publication date:
2009-01-05
DOI:
EISSN:
1538-3687
ISSN:
0003-9942
URN:
uuid:9a74c58c-a5ac-430e-aea6-15c63d9c1f92
Source identifiers:
40999
Local pid:
pubs:40999

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