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The AIP (aryl hydrocarbon receptor-interacting protein) gene and its relation to the pathogenesis of pituitary adenomas

Abstract:

Pituitary adenomas are monoclonal neoplasms that may secrete excessive quantities of their endogenous hormones, or may not be associated with any obvious syndrome, in which case they are known as non-functioning pituitary adenomas. Around 2 % have been said to occur in a familial setting, in the absence of any other tumor, now described as familial isolated pituitary adenomas (FIPA). Some 15-30 % of such families harbor inactivating germ-line mutations in the aryl hydrocarbon receptor-interac...

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Publisher copy:
10.1007/s12020-013-0125-6

Authors


Publisher:
Humana Press Inc.
Journal:
Endocrine
Volume:
46
Issue:
3
Pages:
387-396
Publication date:
2014-01-01
DOI:
EISSN:
1559-0100
ISSN:
1355-008X
URN:
uuid:9a5bf055-32d0-49a4-a4e3-e1c1d794c726
Source identifiers:
478367
Local pid:
pubs:478367
Language:
English
Keywords:

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