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Unique immunobullous disease in a child with a predominantly IgA response to three desmosomal proteins.

Abstract:

We report the case of a 15-year-old girl who presented at 11 years of age with an interesting, acquired and, to our knowledge, unique blistering disease. It involved both skin and mucous membranes with extensive oral and periungual lesions, clinically resembling paraneoplastic pemphigus. Skin biopsy showed an inflammatory cell infiltrate in the upper dermis with numerous leucocytoclastic nuclear fragments, neutrophilic papillary microabscesses and a small subepidermal bulla. Direct and indire...

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Publication status:
Published

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Authors


Mendelsohn, S More by this author
Hashimoto, T More by this author
Nishikawa, T More by this author
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Journal:
The British journal of dermatology
Volume:
141
Issue:
5
Pages:
882-886
Publication date:
1999-11-05
DOI:
EISSN:
1365-2133
ISSN:
0007-0963
URN:
uuid:9a33d743-6e6f-44a9-a8c4-61fe30f02a04
Source identifiers:
13596
Local pid:
pubs:13596

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