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A polymorphism in the glucokinase gene that raises plasma fasting glucose, rs1799884, is associated with diabetes mellitus and prostate cancer: findings from a population-based, case-control study (the ProtecT study).

Abstract:

Epidemiological studies have identified a positive association between prostate cancer and recent onset type 2 diabetes mellitus but an increasingly inverse association with greater duration of type 2 diabetes. The mecha- nisms underlying these paradoxical associations are not clear. A single nucleotide polymorphism in the glucokinase gene, rs1799884, is associated with higher circulating plasma fasting glucose and with an increased risk of type 2 diabetes. We report a case-control study nest...

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Donovan, JL More by this author
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Journal:
International journal of molecular epidemiology and genetics
Volume:
1
Issue:
3
Pages:
175-183
Publication date:
2010
EISSN:
1948-1756
URN:
uuid:9a287bab-67ce-4bad-bbe3-8b8169be85ce
Source identifiers:
121056
Local pid:
pubs:121056

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