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Monitoring response to anti-angiogenic mTOR inhibitor therapy in vivo using (111)In-bevacizumab.

Abstract:

BACKGROUND: The ability to image vascular endothelial growth factor (VEGF) could enable prospective, non-invasive monitoring of patients receiving anti-angiogenic therapy. This study investigates the specificity and pharmacokinetics of (111)In-bevacizumab binding to VEGF and its use for assessing response t...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s13550-017-0297-9

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Department:
Oxford, MSD, Oncology, CRUK/MRC Ox Inst for Radiation Oncology
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Department:
Oxford, MSD, Oncology, CRUK/MRC Ox Inst for Radiation Oncology
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Department:
Oxford, MSD, Oncology, CRUK/MRC Ox Inst for Radiation Oncology
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Department:
Oxford, MSD, Oncology, CRUK/MRC Ox Inst for Radiation Oncology
More by this author
Department:
Oxford, MSD, Oncology, CRUK/MRC Ox Inst for Radiation Oncology
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EPSRC/CRUK Oxford Cancer Imaging Centre More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
EJNMMI Research Journal website
Volume:
7
Issue:
49
Pages:
1-9
Publication date:
2017-05-30
Acceptance date:
2017-05-19
DOI:
ISSN:
2191-219X
Pubs id:
pubs:697959
URN:
uri:9a1e6204-da92-4032-8d61-7b8679c09637
UUID:
uuid:9a1e6204-da92-4032-8d61-7b8679c09637
Local pid:
pubs:697959
Language:
English
Keywords:

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