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Requirements for T lymphocyte migration in explanted lymph nodes.

Abstract:

Although the requirements for T lymphocyte homing to lymph nodes (LNs) are well studied, much less is known about the requirements for T lymphocyte locomotion within LNs. Imaging of murine T lymphocyte migration in explanted LNs using two-photon laser-scanning fluorescence microscopy provides an opportunity to systematically study these requirements. We have developed a closed system for imaging an intact LN with controlled temperature, oxygenation, and perfusion rate. Naive T lymphocyte loco...

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Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
178
Issue:
12
Pages:
7747-7755
Publication date:
2007-06-05
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:99ffa518-4935-4be3-9d4b-99f26c9f4f25
Source identifiers:
482596
Local pid:
pubs:482596

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