Journal article icon

Journal article

Human arthroplasty derived macrophages differentiate into osteoclastic bone resorbing cells.

Abstract:

OBJECTIVE: In aseptic loosening, a heavy macrophage response to biomaterial wear particles is commonly found in arthroplasty tissues. The aim of this study was to discover if these cells contribute to the bone resorption of aseptic loosening by differentiating into osteoclasts. METHODS: Macrophages were isolated from the pseudocapsule and pseudomembrane of loose cemented and uncemented hip arthroplasties at the time of revision surgery and then co-cultured on glass coverslips and dentine slic...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1136/ard.56.7.414

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
Annals of the rheumatic diseases
Volume:
56
Issue:
7
Pages:
414-420
Publication date:
1997-07-05
DOI:
EISSN:
1468-2060
ISSN:
0003-4967
URN:
uuid:99d20949-2b62-467c-9389-4e7ddc1800a1
Source identifiers:
62670
Local pid:
pubs:62670

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP