- Abstract:
-
OBJECTIVE: In aseptic loosening, a heavy macrophage response to biomaterial wear particles is commonly found in arthroplasty tissues. The aim of this study was to discover if these cells contribute to the bone resorption of aseptic loosening by differentiating into osteoclasts. METHODS: Macrophages were isolated from the pseudocapsule and pseudomembrane of loose cemented and uncemented hip arthroplasties at the time of revision surgery and then co-cultured on glass coverslips and dentine slic...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1136/ard.56.7.414
-
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- Journal:
- Annals of the rheumatic diseases
- Volume:
- 56
- Issue:
- 7
- Pages:
- 414-420
- Publication date:
- 1997-07-05
- DOI:
- EISSN:
-
1468-2060
- ISSN:
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0003-4967
- URN:
-
uuid:99d20949-2b62-467c-9389-4e7ddc1800a1
- Source identifiers:
-
62670
- Local pid:
- pubs:62670
- Copyright date:
- 1997
Journal article
Human arthroplasty derived macrophages differentiate into osteoclastic bone resorbing cells.
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