Neuronal pathways in tendon healing and tendinopathy--update.

Journal article

The regulatory mechanisms involved in tendon homeostasis and repair are not fully understood. Accumulating data, however, demonstrate that the nervous system, in addition to afferent (sensory) functions, through efferent pathways plays an active role in regulating pain, inflammation, and tissue repair. In normal-, healing- and tendinopathic tendons three neurosignalling pathways consisting of autonomic, sensory and glutamatergic neuromediators have been established. In healthy tendons, neurom...

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Authors: Ackermann, P; Franklin, S; Dean, B; Carr, A; Salo, P

• Publication status: Published
• Journal: Frontiers in bioscience (Landmark edition)
• Volume: 19
• Issue: 8
• Pages: 1251-1278
• Publication date: 2014-01-01
• DOI: 10.2741/4280
• EISSN: 1093-4715
• ISSN: 1093-9946
• Language: English
• Keywords: Tendon; Review; Neurotransmitters; Pain; Opioids; Glutamate; Tendinopathy; Healing; Neuropeptides