- Abstract:
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Following the poor clinical results of antiangiogenic drugs, particularly when applied in isolation, tumour biologists and clinicians are now turning to combinations of therapies in order to obtain better results. One of these involves vessel normalisation strategies. In this paper, we investigate the effects on tumour growth of combinations of antiangiogenic and standard cytotoxic drugs, taking into account vessel normalisation. An existing multiscale framework is extended to include new ele...
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- Publication date:
- 2006-06-05
- URN:
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uuid:9984e5ee-6b9c-4849-89ca-b16f2206041e
- Local pid:
- oai:eprints.maths.ox.ac.uk:313
- Copyright date:
- 2006
Journal article
Multiscale modelling of tumour growth and therapy: the influence of vessel normalisation on chemotherapy
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