Variability of genome-wide DNA methylation and mRNA expression profiles in reproductive and endocrine disease related tissues
Genome-wide-association-studies in the fields of reproductive medicine and endocrinology are yielding robust genetic variants associated with disease. Integrated genomic, transcriptomic and epigenomic molecular profiling studies are a common methodology to understand the biological pathways perturbed by these variants. However, molecular profiling resources do not include the tissue most relevant to many female reproductive traits, endometrium, whilst the parameters influencing variability o...Expand abstract
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- Rahmioglu et al.
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