Journal article
Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions.
- Abstract:
-
Ly108, a glycoprotein of the signaling lymphocytic activation molecule family of cell surface receptors expressed by T, B, NK, and APCs has been shown to have a role in NK cell cytotoxicity and T cell cytokine responses. In this study, we describe that CD4(+) T cells from mice with a targeted disruption of exons 2 and 3 of Ly108 (Ly108(DeltaE2+3)) produce significantly less IL-4 than wild-type CD4(+) cells, as judged by in vitro assays and by in vivo responses to cutaneous infection with Leis...
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- Publication status:
- Published
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- Publisher copy:
- 10.4049/jimmunol.174.10.5931
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Authors
Bibliographic Details
- Journal:
- Journal of Immunology
- Volume:
- 174
- Issue:
- 10
- Pages:
- 5931-5935
- Publication date:
- 2005-05-01
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Source identifiers:
-
55457
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:55457
- UUID:
-
uuid:99489ac4-0617-463a-94a3-5d84a25dcb36
- Local pid:
- pubs:55457
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2005
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