Journal article icon

Journal article

The impact project: Improving the impact of existing malaria products – Acts

Abstract:

The antimalarial dihydroartemisinin-piperaquine (DHA-PPQ) is one of the recommended drugs to treat uncomplicated Plasmodium falciparum malaria. However, DHA-PPQ has a relatively narrow, poorly defined therapeutic dose range and it is unclear whether PPQ concentration-dependent cardiotoxicity (QTc prolongation) poses a clinical risk for specific subgroups. Uncertainty about the exact safe upper PPQ concentration threshold and recognition of the vulnerability of children has led WHO to consider...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1136/bmjgh-2016-000260.66

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Expand authors...
Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Global Health Journal website
Volume:
2
Issue:
Suppl 2
Pages:
A26.1-A26
Publication date:
2017-02-01
Acceptance date:
2016-08-15
DOI:
ISSN:
2059-7908
Source identifiers:
745818
Pubs id:
pubs:745818
UUID:
uuid:99370a1b-da52-4151-98b2-d8557720fd8b
Local pid:
pubs:745818
Deposit date:
2018-01-25

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP