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Journal article

Expansion of protective CD8+ T-cell responses driven by recombinant cytomegaloviruses.

Abstract:

CD8(+) T cells are critical for the control of many persistent viral infections, such as human immunodeficiency virus, hepatitis C virus, Epstein-Barr virus, and cytomegalovirus (CMV). In most infections, large CD8(+)-T-cell populations are induced early but then contract and are maintained thereafter at lower levels. In contrast, CD8(+) T cells specific for murine CMV (MCMV) have been shown to gradually accumulate after resolution of primary infection. This unique behavior is restricted to c...

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Publication status:
Published

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Journal:
Journal of virology
Volume:
78
Issue:
5
Pages:
2255-2264
Publication date:
2004-03-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:99151c8a-7caa-48f5-8012-dfc533e2d5e7
Source identifiers:
7788
Local pid:
pubs:7788

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