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Confirmation of association of chromosome 5q31-33 with United Kingdom Caucasian Graves' disease.

Abstract:

BACKGROUND: Previous genome-wide microsatellite screening in Graves' disease (GD) has suggested several regions of linkage to disease. Although replication has been inconsistent, some regions such as chromosome 5q31-33 have been associated with several Oriental GD patient cohorts. Recently, two studies have reported association of single-nucleotide polymorphism (SNP) rs31480 in interleukin 3 (IL-3) and the rs1368408 and SNP75 (-623 approximately -622 AG/-T) SNPs in secretoglobulin family 3a ...

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Publisher copy:
10.1089/thy.2009.0375

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM
Franklyn, JA More by this author
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Journal:
Thyroid : official journal of the American Thyroid Association
Volume:
20
Issue:
4
Pages:
413-417
Publication date:
2010-04-05
DOI:
EISSN:
1557-9077
ISSN:
1050-7256
URN:
uuid:991119cc-6377-4dce-b5a7-988b167a83bb
Source identifiers:
176426
Local pid:
pubs:176426

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