- Abstract:
-
The head twitch response in mice produced by injection of 5-hydroxytryptophan (100 mg/kg i.p.) and carbidopa (25 mg/kg i.p.) was enhanced by administration of clenbuterol (0.5 mg/kg i.p.), a beta-adrenoceptor agonist. Clenbuterol also enhanced the hyperactivity syndrome in rats produced by quipazine (25 mg/kg i.p.), a 5-hydroxytryptamine (5-HT) agonist. This enhancement was not prevented by depletion of 5-HT in brain with p-chlorophenylalanine or after pretreatment with prazosin. The behaviou...
Expand abstract - Publication status:
- Published
- Journal:
- Neuropharmacology
- Volume:
- 22
- Issue:
- 6
- Pages:
- 739-749
- Publication date:
- 1983-06-05
- DOI:
- EISSN:
-
1873-7064
- ISSN:
-
0028-3908
- URN:
-
uuid:98faf93b-aee9-4567-9889-45a83c79b0b2
- Source identifiers:
-
185954
- Local pid:
- pubs:185954
- Copyright date:
- 1983
Journal article
Studies on the mechanisms by which clenbuterol, a beta-adrenoceptor agonist, enhances 5-HT-mediated behaviour and increases metabolism of 5-HT in the brain of the rat.
Actions
Authors
Bibliographic Details
Item Description
Terms of use
Metrics
Altmetrics
Dimensions
If you are the owner of this record, you can report an update to it here: Report update to this record