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CD90(+) Stromal Cells are Non-Professional Innate Immune Effectors of the Human Colonic Mucosa.

Abstract:

Immune responses at the intestinal mucosa must allow for host protection whilst simultaneously avoiding inappropriate inflammation. Although much work has focused on the innate immune functionality of hematopoietic immune cells, non-hematopoietic cell populations - including epithelial and stromal cells - are now recognized as playing a key role in innate defense at this site. In this study we examined the innate immune capacity of primary human intestinal stromal cells (iSCs). CD90(+) iSCs i...

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Publisher copy:
10.3389/fimmu.2013.00307

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
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Journal:
Frontiers in immunology
Volume:
4
Issue:
SEP
Pages:
307
Publication date:
2013-01-01
DOI:
EISSN:
1664-3224
URN:
uuid:98b5ca16-6d78-4019-b213-343ff2c6620b
Source identifiers:
434133
Local pid:
pubs:434133

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