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Journal article

Association of low-density lipoprotein receptor polymorphisms and outcome of hepatitis C infection.

Abstract:

The low-density lipoprotein receptor (LDLR) has been proposed to promote hepatitis C virus endocytosis and the cell membrane protein CD81 may also promote HCV host cell entry. The CD81 gene was sequenced to screen for novel polymorphisms, but no SNPs were identified. Polymorphisms within the LDLR gene are associated with the pathogenesis of familial hypercholesterolemia, atherosclerosis and obesity. We therefore studied genetic variation within the LDLR gene and clinical features of hepatitis...

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Publication status:
Published

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Publisher copy:
10.1038/sj.gene.6363883

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division, Biomedical Research Centre
Role:
Author
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Journal:
Genes and immunity
Volume:
3
Issue:
6
Pages:
359-367
Publication date:
2002-09-05
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
URN:
uuid:98a9ab89-a0e4-46b9-a096-b0feb9554c00
Source identifiers:
27436
Local pid:
pubs:27436

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