Journal article icon

Journal article : Review

(ADP-ribosyl)hydrolases: structure, function, and biology

Abstract:

ADP-ribosylation is an intricate and versatile posttranslational modification involved in the regulation of a vast variety of cellular processes in all kingdoms of life. Its complexity derives from the varied range of different chemical linkages, including to several amino acid side chains as well as nucleic acids termini and bases, it can adopt. In this review, we provide an overview of the different families of (ADP-ribosyl)hydrolases. We discuss their molecular functions, physiological rol...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1101/gad.334631.119

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
ORCID:
0000-0001-8341-6439
More by this author
Role:
Author
ORCID:
0000-0002-5556-5549
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
ORCID:
0000-0002-9446-3756
Publisher:
Cold Spring Harbor Laboratory Press
Journal:
Genes and Development More from this journal
Volume:
34
Issue:
5-6
Pages:
263-284
Publication date:
2020-02-06
Acceptance date:
2019-12-23
DOI:
EISSN:
1549-5477
ISSN:
0890-9369
Pmid:
32029451
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1087457
Local pid:
pubs:1087457
Deposit date:
2021-07-14

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP