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Journal article

Dysfunctional prefrontal cortical network activity and interactions following cannabinoid receptor activation.

Abstract:

Coordinated activity spanning anatomically distributed neuronal networks underpins cognition and mediates limbic-cortical interactions during learning, memory, and decision-making. We used CP55940, a potent agonist of brain cannabinoid receptors known to disrupt coordinated activity in hippocampus, to investigate the roles of network oscillations during hippocampal and medial prefrontal cortical (mPFC) interactions in rats. During quiet wakefulness and rest, CP55940 dose-dependently reduced 0...

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Publication status:
Published

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Authors


Kucewicz, MT More by this author
Tricklebank, MD More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
31
Issue:
43
Pages:
15560-15568
Publication date:
2011-10-05
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:988493a9-7bf4-4f9b-875f-77e1bd1974b2
Source identifiers:
420759
Local pid:
pubs:420759

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