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Cell transplantation strategies for retinal repair.

Abstract:

Cell transplantation is a novel therapeutic strategy to restore visual responses to the degenerate adult neural retina and represents an exciting area of regenerative neurotherapy. So far, it has been shown that transplanted postmitotic photoreceptor precursors are able to functionally integrate into the adult mouse neural retina. In this review, we discuss the differentiation of photoreceptor cells from both adult and embryonic-derived stem cells and their potential for retinal cell transpla...

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Authors


Pearson, RA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Sowden, JC More by this author
Journal:
Progress in brain research
Volume:
175
Pages:
3-21
Publication date:
2009
DOI:
EISSN:
1875-7855
ISSN:
0079-6123
URN:
uuid:985e6eaf-0858-4b5d-b48d-3bee53d11556
Source identifiers:
107262
Local pid:
pubs:107262

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