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Prospects for improving neovascularization of the ischemic heart: Lessons from development.

Abstract:

Neovascularization of the ischemic myocardium postinfarction is necessary to restore blood flow to vulnerable cardiomyocytes and will be indispensable for prospective regenerative strategies, to perfuse newly formed myocardium. Therapeutic attempts to enhance new vessel formation have, to date, yielded modest clinical benefits, and innovative approaches are now needed. Intrinsic mechanisms are initiated by the heart in an attempt to rebuild injured vessels, but these are poorly understood. In...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1111/micc.12335

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Institution:
University of Oxford
Department:
All Souls College
Role:
Author
Publisher:
Wiley Publisher's website
Journal:
Microcirculation Journal website
Volume:
24
Issue:
1
Pages:
e12335
Publication date:
2016-11-17
Acceptance date:
2016-11-14
DOI:
EISSN:
1549-8719
ISSN:
1073-9688
Pubs id:
pubs:664158
URN:
uri:985cb895-457c-48f8-87fd-5a4d162a297e
UUID:
uuid:985cb895-457c-48f8-87fd-5a4d162a297e
Local pid:
pubs:664158
Paper number:
1

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