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Proteomic analysis of colony morphology variants of Burkholderia pseudomallei defines a role for the arginine deiminase system in bacterial survival.

Abstract:

Colony morphology variation of Burkholderia pseudomallei is a notable feature of a proportion of primary clinical cultures from patients with melioidosis. Here, we examined the hypothesis that colony morphology switching results in phenotypic changes associated with enhanced survival under adverse conditions. We generated isogenic colony morphology types II and III from B. pseudomallei strain 153 type I, and compared their protein expression profiles using 2D gel electrophoresis. Numerous pro...

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Publication status:
Published

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Publisher copy:
10.1016/j.jprot.2011.10.015

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Tandhavanant, S More by this author
Wikraiphat, C More by this author
Trunck, LA More by this author
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Journal:
Journal of proteomics
Volume:
75
Issue:
3
Pages:
1031-1042
Publication date:
2012-01-05
DOI:
EISSN:
1876-7737
ISSN:
1874-3919
URN:
uuid:9854b8b7-023d-4f7c-9ac1-0ef779a955ad
Source identifiers:
198796
Local pid:
pubs:198796

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