OBJECTIVE: The number of confirmed rheumatoid arthritis (RA) loci currently stands at 32, but many lines of evidence indicate that expansion of existing genome-wide association studies (GWAS) enhances the power to detect additional loci. This study was undertaken to extend our previous RA GWAS in a UK cohort, adding more independent RA cases and healthy controls, with the aim of detecting novel association signals for susceptibility to RA in a homogeneous UK cohort. METHODS: A total of 3,223 ...Expand abstract
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- John Wiley and Sons Inc.
- Arthritis and rheumatology (Hoboken, N.J.)
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Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.
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