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Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.

Abstract:

OBJECTIVE: The number of confirmed rheumatoid arthritis (RA) loci currently stands at 32, but many lines of evidence indicate that expansion of existing genome-wide association studies (GWAS) enhances the power to detect additional loci. This study was undertaken to extend our previous RA GWAS in a UK cohort, adding more independent RA cases and healthy controls, with the aim of detecting novel association signals for susceptibility to RA in a homogeneous UK cohort. METHODS: A total of 3,223 ...

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Publication status:
Published

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Publisher copy:
10.1002/art.38196

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Publisher:
John Wiley and Sons Inc.
Journal:
Arthritis and rheumatology (Hoboken, N.J.)
Volume:
66
Issue:
1
Pages:
24-30
Publication date:
2014-01-05
DOI:
EISSN:
2326-5205
ISSN:
2326-5191
URN:
uuid:9852f856-2550-4b5c-a1dc-6670cf77bda8
Source identifiers:
466365
Local pid:
pubs:466365

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