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Effect of Vitamin D supplementation on synovial tissue volume and subchondral bone marrow lesion volume in symptomatic knee osteoarthritis

Abstract:

Background Data from a recent clinical trial of vitamin D therapy in knee OA suggests that, compared to placebo, vitamin D therapy may be associated with a reduction in effusion-synovitis. Our aim was, using contrast-enhanced (CE) magnetic resonance imaging (MRI), to examine the effect of vitamin D therapy on synovial tissue volume (STV) and also subchondral bone marrow lesion (BML) volume in men and women with symptomatic knee OA. Methods Data was acquired from participants who took part in...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1186/s12891-019-2424-4

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Subgroup:
Botnar Research Centre
ORCID:
0000-0002-0499-3033
Parkes, MJ More by this author
Hodgson, R More by this author
Felson, DT More by this author
O’Neill, TW More by this author
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Publisher:
BMC Publisher's website
Journal:
BMC Musculoskeletal Disorders Journal website
Volume:
20
Pages:
Article: 76
Publication date:
2019-02-14
Acceptance date:
2019-01-18
DOI:
ISSN:
1471-2474
Pubs id:
pubs:974323
URN:
uri:9851a123-878a-42a5-95f9-3b3ee4dfa42f
UUID:
uuid:9851a123-878a-42a5-95f9-3b3ee4dfa42f
Local pid:
pubs:974323
Language:
English

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