Journal article
Engaging neuroscience to advance translational research in brain barrier biology.
- Abstract:
- The delivery of many potentially therapeutic and diagnostic compounds to specific areas of the brain is restricted by brain barriers, of which the most well known are the blood-brain barrier (BBB) and the blood-cerebrospinal fluid (CSF) barrier. Recent studies have shown numerous additional roles of these barriers, including an involvement in neurodevelopment, in the control of cerebral blood flow, and--when barrier integrity is impaired--in the pathology of many common CNS disorders such as Alzheimer's disease, Parkinson's disease and stroke.
- Publication status:
- Published
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- Publisher copy:
- 10.1038/nrn2995
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Bibliographic Details
- Journal:
- Nature reviews. Neuroscience
- Volume:
- 12
- Issue:
- 3
- Pages:
- 169-182
- Publication date:
- 2011-03-01
- DOI:
- EISSN:
-
1471-0048
- ISSN:
-
1471-003X
- Source identifiers:
-
124494
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:124494
- UUID:
-
uuid:981e0fb3-04d4-4c5f-9c33-9f9b88fed2eb
- Local pid:
- pubs:124494
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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