Thesis icon

Thesis

Plasticity associated with Up/Down states in the mouse barrel cortex

Abstract:

Slow wave sleep is characterised by synchronised slow oscillations, which manifest themselves in cortical neurons as depolarised Up states and more hyperpolarised, silent Down states. Up/Down states have been implicated in synaptic plasticity during sleep-associated memory consolidation. However, the underlying mechanism is not well-understood.

I used the mouse somatosensory barrel cortex as a model system to investigate whether Up states and Down states differentially facilitate sy...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author

Contributors

Role:
Supervisor
Wellcome Trust More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:980a4f39-d60c-4484-a09f-3765ca6063d6
Deposit date:
2017-06-27

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP