Radiolabelling of aryl boronic esters with 18F and 123I: method development and application
The overarching theme of this thesis is the application of aryl boronic esters to the fields of PET and SPECT radiochemistry.
Chapter 1 provides an introduction to positron emission tomography (PET) and single photon emission computed tomography (SPECT), in conjunction with an introduction to the utility of arylboranes as precursors for radioisotope incorporation.
In chapter 2, a general method for the copper-mediated nucleophilic 123I-iodination of...Expand abstract
- Type of award:
- Level of award:
- Awarding institution:
- University of Oxford
- Copyright date: