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Burkholderia pseudomallei genome plasticity associated with genomic island variation.

Abstract:

BACKGROUND: Burkholderia pseudomallei is a soil-dwelling saprophyte and the cause of melioidosis. Horizontal gene transfer contributes to the genetic diversity of this pathogen and may be an important determinant of virulence potential. The genome contains genomic island (GI) regions that encode a broad array of functions. Although there is some evidence for the variable distribution of genomic islands in B. pseudomallei isolates, little is known about the extent of variation between related...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2164-9-190

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Funding agency for:
Peacock, S
Grant:
Career Development Award in Clinical Tropical Medicine
Wellcome Trust More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
BMC genomics Journal website
Volume:
9
Issue:
1
Pages:
Article no. 190
Publication date:
2008-01-01
DOI:
EISSN:
1471-2164
ISSN:
1471-2164
Source identifiers:
26275
Language:
English
Keywords:
UUID:
uuid:97feea0c-d043-4001-86e2-18a7cdeca0b1
Local pid:
pubs:26275
Deposit date:
2012-12-19

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