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Susceptibility to dengue hemorrhagic fever in vietnam: evidence of an association with variation in the vitamin d receptor and Fc gamma receptor IIa genes.

Abstract:

Dengue is an increasingly important cause of morbidity and mortality in the tropics, with more than a billion people at risk each year. Immunologic enhancement is thought to contribute to disease pathogenesis. Only a very small proportion of infected individuals develop life-threatening dengue hemorrhagic fever (DHF). In a large case-control study with 400 DHF patients and 300 matched controls, we have assessed five polymorphic non-HLA host genetic factors that might influence susceptibility ...

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Publication status:
Published

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Authors


Bethell, D More by this author
Phuong, CX More by this author
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Journal:
The American journal of tropical medicine and hygiene
Volume:
67
Issue:
1
Pages:
102-106
Publication date:
2002-07-05
EISSN:
1476-1645
ISSN:
0002-9637
URN:
uuid:97fe7222-f372-4678-8589-fd511c50037f
Source identifiers:
32219
Local pid:
pubs:32219

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